Eicosapentaenoic Acid and Docosahexsaenoic Acid

Eicosapentaenoic Acid in Diabetes

63 Received July 12, 2013; revised and accepted September 3, 2013. Published online September 25, 2013; doi: 10.1620/tjem.231.63. Correspondence: Susumu Ogawa, M.D., Ph.D., Division of Nephrology, Endocrinology and Vascular Medicine, Tohoku University Hospital, 1-1, Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8574, Japan. e-mail: [email protected] Eicosapentaenoic Acid Improves Glycemic C...

Enhanced heterologous production of eicosapentaenoic acid in Escherichia coli cells that coexpress eicosapentaenoic acid biosy

Cellular eicosapentaenoic acid (EPA) makes up approximately 3% of total fatty acids in Escherichia coli DH5α, a strain that carries EPA biosynthesis genes (pEPAΔ1). EPA was increased to 12% of total fatty acids when the host cell coexpressed the vector pGBM3::sa1(vktA), which carried the high-performance catalase gene, vktA. Where this vector was coexpressed, the transformant accumulated a larg...

Anticachectic and Antitumor Effect of Eicosapentaenoic Acid

The effect of the polyunsaturated fatty acids eicosapentaenoic acid (EPA) and 7-linolenic acid (GLA) on host body weight loss and tumor growth has been investigated in mice bearing a cachexia-inducing colon adenocarcinoma, the MAC16. EPA effectively inhibited both host weight loss and tumor growth rate in a dose-related manner with optimal effects being observed at a dose level of 1.25 to 2.5 g...

Stearidonic acid raises red blood cell membrane eicosapentaenoic acid.

The consumption of EPA and DHA has been associated with reduced risk for cardiovascular disease morbidity and mortality. Mean intakes of EPA and DHA in the United States and elsewhere are below levels recommended by health authorities. The main non-marine source of dietary (n-3) fatty acids (α-linolenic acid) is poorly converted to EPA in humans. Stearidonic acid (SDA) is a non-marine fatty aci...

P-200: Effects of The ?3 Fatty Acid Eicosapentaenoic Acid on PPARa and Aromatase in Human Granulosa Cells